Hydroxychloroquine (DMARD) - Pharmacology, mechanism of action, indication, side effects

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"Hydroxychloroquine (plaquenil) is an old antimalarial agent that has immunomodulatory effects widely used in SLE, in which it decreases mortality and the likelihood of developing lupus nephritis, a very common complication of SLE. It works by inhibiting the processing effects of peptide antigens and their assembly into major histocompatibility complex by antigen presenting cells."

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